Pure-Fit SIB Manifolds

Pure-Fit SIB is a smooth inner bore (SIB) manifolding system that provides a seamless transition of tubing and fittings, maintaining complete fluid integrity throughout the system. Quick and secure connections, as well as the prevention of fluid contamination and product loss through leakage, are critical in biopharmaceutical applications. Pure-Fit SIB, with its patented 360° compression seal, is the solution to these potential problems.

Pure-Fit SIB’s unique internal design reduces the risk of tubing being punctured or cut from sharp, barbed edges like those on traditional fitting systems. Because of the smooth inner bore design, Pure-Fit SIB eliminates turbulence (dead space) or stagnation of fluid flow, which creates areas for potential bacteria growth.

The Pure-Fit SIB system is ideal for making single-use manifolds. It offers more flexibility than molded manifolds. Pure-Fit SIB fittings systems are compatible with all of our silicone tube offerings as well as TPE tube including C-Flex. Manifolds can be assembled in-house. Holland Applied Technologies also offers manifold assembly services, including clean room assembly and gamma irradiation.

Product Features:

  • Total smooth inner bore (SIB®) transition design
  • Eliminates entrapment and leak points that occur with traditional fitting systems
  • Complete 360° compression along the entire fitting system
  • No excessive voids at the interface or in the fluid path
  • Utilizes the patented retention and seal system
  • Compatible with all flexible tubing
  • Complete customized manifold and assembly systems
  • Autoclavable and sterilizable
  • Available in polypropylene or PVDF
  • All materials completely animal-free and BPA free
  • Manufactured and packaged in a certified clean room

Product Documents

Pure-Fit SIB Brochure


Pure-Fit SIB fitting systems meet all USP Class VI criteria and have been physically tested to meet the most demanding applications.

Pure-Fit SIB Typical Physical Properties

Tensile Strength,psi (MPa) ASTM D638-914,800 (33.1)6,300 (43.4)
Flexural Modulus,psi (MPa) ASTM D790-92145,000 (999.7)290,000 (1,999.5)
Hardness (Shore D)ASTM D2240-917278
Heat Deflection ASTM D648-82 ºF (ºC) @66 psiºF (ºC) @264 psi189 (87)—266 (130) 221 (105)
Water Absorption (%)ASTM D570-810.010.03
Max. Recommended Working Temp., ºF (ºC)200 (93)275 (135)

Animal Free Polypropylene Pure-Fit SIB Part Numbers and Pressure Ratings

Part NumberConfigurationTubing IDMax Presure @72°FMax Presure @200°F
PFY250PPAFWye1/4250 psi100 psi
PFT250PPAFTee1/4250 psi100 psi
PFX250PPAFCross1/4250 psi100 psi
PFE250PPAFElbow1/4250 psi100 psi
PFLS250PPAFTri-clamp1/4250 psi100 psi
PFMS250PPAFMini1/4250 psi100 psi
PF135250PPAFRetainer1/4250 psi100 psi
PFY375PPAFWye3/8250 psi100 psi
PFT375PPAFTee3/8250 psi100 psi
PFX375PPAFCross3/8250 psi100 psi
PFE375PPAFElbow3/8250 psi100 psi
PFLS375PPAFTri-clamp3/8250 psi100 psi
PFMS375PPAFMini3/8250 psi100 psi
PF135375PPAFRetainer3/8250 psi100 psi
PFY500PPAFWye1/2250 psi100 psi
PFT500PPAFTee1/2250 psi100 psi
PFX500PPAFCross1/2250 psi100 psi
PFE500PPAFElbow1/2250 psi100 psi
PFLS500PPAFTri-clamp1/2250 psi100 psi
PFMS500PPAFMini1/2250 psi100 psi
PF135500PPAFRetainer1/2250 psi100 psi

PVDF Pure-Fit SIB Part Numbers and Pressure Ratings

Part NumberConfigurationTubing IDMax Presure @72°FMax Presure @200°F
PFY250PVDFWye1/4250 psi100 psi
PFT250PVDFTee1/4250 psi100 psi
PFX250PVDFCross1/4250 psi100 psi
PFE250PVDFElbow1/4250 psi100 psi
PFLS250PVDFTri-clamp1/4250 psi100 psi
PFMS250PVDFMini1/4250 psi100 psi
PF135250PVDFRetainer1/4250 psi100 psi
PFY375PVDFWye3/8250 psi100 psi
PFT375PVDFTee3/8250 psi100 psi
PFX375PVDFCross3/8250 psi100 psi
PFE375PVDFElbow3/8250 psi100 psi
PFLS375PVDFTri-clamp3/8250 psi100 psi
PFMS375PVDFMini3/8250 psi100 psi
PF135375PVDFRetainer3/8250 psi100 psi
PFY500PVDFWye1/2250 psi100 psi
PFT500PVDFTee1/2250 psi100 psi
PFX500PVDFCross1/2250 psi100 psi
PFE500PVDFElbow1/2250 psi100 psi
PFLS500PVDFTri-clamp1/2250 psi100 psi
PFMS500PVDFMini1/2250 psi100 psi
PF135500PVDFRetainer1/2250 psi100 psi